Aeruginosins 102-A and B, new thrombin inhibitors from the cyanobacterium Microcystis viridis (NIES-102)

Aeruginosins 102-A and B, new thrombin inhibitors from the cyanobacterium Microcystis viridis (NIES-102)
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DOI:
10.1016/0040-4020(96)00890-3
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发表时间:
1996-11-11
期刊:
影响因子:
2.1
通讯作者:
Yamaguchi, K
Yamaguchi, K
中科院分区:
化学3区
文献类型:
--
作者:
Matsuda, H;Okino, T;Yamaguchi, K

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从淡水蓝藻铜绿微囊藻(Microcystis aeruginosa,NIES-102)中分离得到Aerodynosins 102-A和B。根据2D NMR数据和化学降解结果,将它们的结构鉴定为1和2。这些肽有效地抑制凝血酶。版权所有(C)1996 Elsevier Science Ltd
Aeruginosins 102-A and B were isolated from the freshwater cyanobacterium Microcystis aeruginosa (NIES-102). Their structures were elucidated to be 1 and 2 on the basis of 2D NMR data and chemical degradation. These peptides inhibited thrombin potently. Copyright (C) 1996 Elsevier Science Ltd