CORONARY-PRONE BEHAVIORS IN THE WESTERN-COLLABORATIVE-GROUP STUDY
CORONARY-PRONE BEHAVIORS IN THE WESTERN-COLLABORATIVE-GROUP STUDY
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DOI：
10.1097/00006842-198803000-00005
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发表时间：
1988-03-01
影响因子：
3.3
通讯作者：
FRAUTSCHI, N
中科院分区：
文献类型：
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作者：
HECKER, MHL;CHESNEY, MA;FRAUTSCHI, N
研究人员对来自西方协作组研究的 250 例 CHD 病例和 500 例匹配对照进行了研究，以评估特定行为维度与冠心病发病率的 8.5 年前瞻性关系。入学时进行的 A 型结构性访谈根据 12 个可操作定义的组成部分进行了重新评估，其中包括之前描述的 A 型行为模式的各个方面。使用匹配逻辑模型的单变量风险分析发现，敌意（RR = 1.92，p < 0.001）、语速（RR = 1.66，p = 0.003）、即时性（RR = 1.62，p = 0.009）、竞争力（RR = 1.50，p = 0.013）和A类内容（RR = 1.38，p = 0.045）与冠心病的发生显着相关。当所有 12 个成分都包含在模型中时，其中只有敌意仍然是显着的风险因素（RR = 1.93，p < 0.001）。原始A类全球评级和传统CHD风险因素也结合成分进行了分析。 A 型行为模式包括良性和冠状动脉倾向方面，后者以敌意为例证。
Two-hundred-fifty CHD cases and 500 matched controls from the Western Collaborative Group Study were studied to assess the 8.5-yr prospective relationship of specific behavioral dimensions to the incidence of coronary heart disease. Type A structural interviews administered at intake were reevaluated in terms of 12 operationally defined components, which include previously described facets of the Type A behaviour pattern. Univariate risk analyses using the matched logistic model found hostility (RR = 1.92, p < 0.001), speaking rate (RR = 1.66, p = 0.003), immediateness (RR = 1.62, p = 0.009), competitiveness (RR = 1.50, p = 0.013), and Type A content (RR = 1.38, p = 0.045) to be significantly related to CHD incidence. Of these, only hostility remained a significant risk factor (RR = 1.93, p < 0.001) when all 12 components were included in the model. The original Type A global ratings and traditional CHD risk factors were also analyzed in conjunction with the components. The Type A behavior pattern comprises both benign and coronary-prone facets, with the latter mose exemplified by hostility.