Dynamics of West Nile virus evolution in mosquito vectors
Dynamics of West Nile virus evolution in mosquito vectors
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DOI:
10.1016/j.coviro.2016.09.007
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发表时间:
2016-12-01
影响因子:
5.9
通讯作者:
Ebel, Gregory D.
中科院分区:
文献类型:
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作者:
Grubaugh, Nathan D.;Ebel, Gregory D.
West Nile virus remains the most common cause of arboviral encephalitis in North America. Since it was introduced, it has undergone adaptive genetic change as it spread throughout the continent. The WNV transmission cycle is relatively tractable in the laboratory. Thus the virus serves as a convenient model system for studying the population biology of mosquito-borne flaviviruses as they undergo transmission to and from mosquitoes and vertebrates. This review summarizes the current knowledge regarding the population dynamics of this virus within mosquito vectors.