Physical Activity Increases Gains in and Prevents Loss of Physical Function: Results From the Lifestyle Interventions and Independence for Elders Pilot Study

Physical Activity Increases Gains in and Prevents Loss of Physical Function: Results From the Lifestyle Interventions and Independence for Elders Pilot Study
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DOI:
10.1093/gerona/gls186
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发表时间:
2013-04-01
影响因子:
5.1
通讯作者:
Rejeski, W. Jack
Rejeski, W. Jack
中科院分区:
医学1区
文献类型:
--
作者:
Ip, Edward H.;Church, Timothy;Rejeski, W. Jack

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身体活动(PA)似乎对身体功能有积极的影响,然而,研究没有检查身体功能的多个指标,也没有将身体功能概念化为一种状态,而不是一种特质,大约424名年龄为70 - 89岁的男性和女性被随机分配完成PA或成功老龄化(SA)教育计划。在基线、6个月和12个月时评估平衡、步态速度、椅子站立性能、握力和完成400米步行的时间。使用隐马尔可夫模型,身体机能的经验状态,根据这些性能指标的平衡,力量,和流动性。PA和SA之间的身体功能的增益和损失率进行了比较。八种残疾状态被确定并浓缩为四个临床相关的状态。状态1代表身体功能轻度残疾,状态2和3被视为中度残疾,状态4为重度残疾。大约30.1%的参与者在6个月时改变了状态,12个月时为24.1%,两个时间点均为11.0%。与SA组相比,PA组更有可能恢复或维持功能,并且不太可能失去功能。例如,PA参与者比SA参与者保持状态1的可能性高20%。PA似乎对老年人的身体功能动态有有利的影响。
Physical activity (PA) appears to have a positive effect on physical function, however, studies have not examined multiple indices of physical function jointly nor have they conceptualized physical functioning as a state rather than a trait.About 424 men and women aged 7089 were randomly assigned to complete a PA or a successful aging (SA) education program. Balance, gait speed, chair stand performance, grip strength, and time to complete the 400-m walk were assessed at baseline and at 6 and 12 months. Using hidden Markov model, empiric states of physical functioning were derived based on these performance measures of balance, strength, and mobility. Rates of gain and loss in physical function were compared between PA and SA.Eight states of disability were identified and condensed into four clinically relevant states. State 1 represented mild disability with physical functioning, states 2 and 3 were considered intermediate states of disability, and state 4 severe disability. About 30.1% of all participants changed states at 6 months, 24.1% at 12 months, and 11.0% at both time points. The PA group was more likely to regain or sustain functioning and less likely to lose functioning when compared with SA. For example, PA participants were 20% more likely than the SA participants to remain in state 1.PA appears to have a favorable effect on the dynamics of physical functioning in older adults.