Phenotype differences of STRs in 7 human populations
Phenotype differences of STRs in 7 human populations
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7个人群中STR表型差异
DOI：
10.1007/bf01246881
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发表时间：
2005
影响因子：
2.1
通讯作者：
B. Brinkmann
中科院分区：
文献类型：
--
作者：
E. Meyer;P. Wiegand;B. Brinkmann
在7个人群(德国人、土耳其人、摩洛哥人、日本人、中国人、巴布亚人、奥万博斯人)中调查了最多6个STR系统(TH01、VWA、ACTBP2、FES、F13B、D21S11)。在每个种群中没有观察到偏离Hardy-Weinberg平衡的情况。从每个群体中随机选择50个个体(包括3至6个STR)的表型。在表型频率的基础上，利用其他种群的频率进行种群间的比较。在主要种族群体中，仅发现表型频率的微小差异。在主要族裔群体之间，可以观察到高达几个数量级的差异。用于群体间比较的最具区分性的STR是TH01、FES和F13B。
A maximum of 6 STR systems (TH01, VWA, ACTBP2, FES, F13B, D21S11) was investigated in 7 human populations (Germans, Turks, Moroccans, Japanese, Chinese, Papuans, Ovambos). In each population no deviations from Hardy-Weinberg equilibrium were observed. Out of each population the phenotypes of 50 individuals (comprising 3 to 6 STRs) were randomly selected. Based on the phenotype frequencies interpopulation comparisons were carried out using the frequencies of each other population. Within major ethnic groups only minor differences in phenotype frequencies were found. Between major ethnic groups differences of up to several orders of magnitude could be observed. The most discriminative STRs for interpopulation comparisons were TH01, FES and F13B.
F13B 基因座的四核苷酸重复。
影响因子：
14.9
作者：
Nishimura,DY;Murray,JC
通讯作者：
Murray,JC
影响因子：
4.4
作者：
EDWARDS, A;HAMMOND, HA;CHAKRABORTY, R
通讯作者：
CHAKRABORTY, R