DOMINO: a database of domain-peptide interactions

DOMINO: a database of domain-peptide interactions
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DOI:
10.1093/nar/gkl961
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发表时间:
2007-01-01
影响因子:
14.9
通讯作者:
Cesareni, Gianni
Cesareni, Gianni
中科院分区:
生物学2区
文献类型:
--
作者:
Ceol, Arnaud;Chatr-aryamontri, Andrew;Cesareni, Gianni

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许多蛋白质相互作用是通过结合短线性肽的小蛋白质模块介导的。DOMINO (http://mint.bio.uniroma2.it/domino/)是一个开放访问的数据库,包含超过3900个描述由蛋白质相互作用域介导的相互作用的注释实验。可以使用通用的搜索工具搜索DOMINO,并且可以使用方便的图形显示小程序可视化交互网络,该小程序显式地标识交互中涉及的域/站点。
Many protein interactions are mediated by small protein modules binding to short linear peptides. DOMINO (http://mint.bio.uniroma2.it/domino/) is an open-access database comprising more than 3900 annotated experiments describing interactions mediated by protein-interaction domains. DOMINO can be searched with a versatile search tool and the interaction networks can be visualized with a convenient graphic display applet that explicitly identifies the domains/sites involved in the interactions.