Switching Regioselectivity of beta-Ketothioamides by Means of Iodine Catalysis: Synthesis of Thiazolylidenes and 1,4-Dithiines
Switching Regioselectivity of beta-Ketothioamides by Means of Iodine Catalysis: Synthesis of Thiazolylidenes and 1,4-Dithiines
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通过碘催化切换 β-酮硫酰胺的区域选择性：噻唑亚烷基和 1,4-二噻因的合成
DOI：
10.1002/chem.201304497
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发表时间：
2014
期刊：
影响因子：
--
通讯作者：
Li Ming
中科院分区：
文献类型：
--
作者：
Wen Li-Rong;Men Lian-Bin;He Tao;Ji Guo-Jing;Li Ming
以β-酮硫代酰胺（KTA）为原料，通过控制I2的用量，一步合成了噻唑亚基和1，4-二噻烯，并通过[3+2]或[3+3]环化缩合反应，实现了不同级联反应的合成。这些转换的一个可能的机制建议。
An efficient I2‐catalyzed synthesis of thiazolylidenes and 1,4‐dithiines from β‐ketothioamides (KTAs) has been developed by only controlling the amount of I2that triggers different cascade reaction sequences by means of [3+2] or [3+3] cyclocondensation in a one‐step process. A possible mechanistic proposal for these transformations is presented.