NONCOLONIC FEATURES OF IRRITABLE-BOWEL-SYNDROME
NONCOLONIC FEATURES OF IRRITABLE-BOWEL-SYNDROME
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DOI：
10.1136/gut.27.1.37
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发表时间：
1986-01-01
期刊：
影响因子：
24.5
通讯作者：
ROBERTS, CT
中科院分区：
文献类型：
--
作者：
WHORWELL, PJ;MCCALLUM, M;ROBERTS, CT
在100例肠易激综合征患者中，各种各样的非胃肠道症状明显比100例年龄、性别和社会阶层匹配的对照组更常见。夜尿、排尿频率和紧迫性、膀胱排空不完全、背痛、口腔中的不愉快味道、持续的疲劳感和女性性交困难尤其突出（P < 0.0001）。非结肠消化道症状以恶心、呕吐、吞咽困难、早饱最为常见（P < 0.0001）。无论患者是否患有精神疾病，均观察到这种症状多样性。患者吸烟比对照组多（p = 0.02），喝更多含咖啡因的饮料（p = 0.03），26%的人在过去12个月内至少休息一周。33%的患者有肠易激综合征家族史。认识到这些不同的症状可以防止转诊到错误的医学专业和不适当的调查。它们也可能表明比以前认识到的更弥漫性的平滑肌疾病。
In 100 patients with irritable bowel syndrome a wide variety of non-gastrointestinal symptoms were significantly more common than in a group of 100 age, sex, and social class matched controls. Nocturia, frequency and urgency of micturition, incomplete bladder emptying, back pain, an unpleasant taste in the mouth, a constant feeling of tiredness and in women dyspareunia were particularly prominent (P < 0.0001). With reference to non-colonic gastrointestinal symptoms nausea, vomiting, dysphagia and early satiety were very common (P < 0.0001). This symptom diversity was observed irrespective of whether the patient had a psychiatric disorder or not. Patients smoked more than controls (p = 0.02) drank more caffeine containing drinks (p = 0.03) and 26% had taken at least one week off work in the previous 12 months. Thirty three per cent of patients had a family history of irritable bowel syndrome. Cognisance of these diverse symptoms may prevent referral to the wrong medical specialty and inappropriate investigation. They may also be indicative of a much more diffuse disorder of smooth muscle than has previously been appreciated.