PROPOSED NOMENCLATURE IN THE FIELD OF NEURAMINIC AND SIALIC ACIDS
PROPOSED NOMENCLATURE IN THE FIELD OF NEURAMINIC AND SIALIC ACIDS
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DOI：
10.1038/1791088b0
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发表时间：
1957-01-01
期刊：
影响因子：
64.8
通讯作者：
KLENK, E
中科院分区：
文献类型：
--
作者：
BLIX, FG;GOTTSCHALK, A;KLENK, E
看来，以各种名称命名的物质（如神经氨酸、唾液酸、乳酸和雌胺酸）之间的化学关系已经确立。为了避免进一步的混淆，我们建议称这种碱性的、未取代的化合物为神经氨酸。唾液酸建议作为酰化神经氨酸的组名（例如，N-乙酰神经氨酸、N-羟乙酰神经氨酸、二乙酰神经氨酸）。对于分裂将末端唾液酸连接到残余寡糖或多糖的糖苷键的酶，可以同义地使用名称神经氨酸酶和唾液酸酶。我们已同意今后使用这一名称。
IT would appear that the chemical relationship of the substances designated by various names such as neuraminic, sialic, lactiminic and gynaminic acid has been established. In order to avoid further confusion we propose to call the basic, unsubstituted compound neuraminic acid. Sialic acid is suggested as group name for the acylated neuraminic acids (for example, N-acetylneuraminic acid, N-glycolylneuraminic acid, diacetylneuraminic acids). For the enzyme which splits the glycosidic linkage joining the terminal sialic acid to the residual oligo- or polysaccharide the names neuraminidase and sialidase may be used synonymously. We have agreed to use this nomenclature in future.