Cost-Effectiveness of Total Colonoscopy in Screening of Colorectal Cancer in Japan
Cost-Effectiveness of Total Colonoscopy in Screening of Colorectal Cancer in Japan
复制标题
日本全结肠镜检查在结直肠癌筛查中的成本效益
DOI：
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发表时间：
2012
影响因子：
2
通讯作者：
Yutaka Saito
中科院分区：
文献类型：
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作者：
M. Sekiguchi;T. Matsuda;Naoto Tamai;T. Sakamoto;T. Nakajima;Y. Otake;Y. Kakugawa;Y. Murakami;Yutaka Saito
导论.在日本，全结肠镜检查（TCS）用于结直肠癌（CRC）初筛的成本效益尚不清楚。我们比较了使用TCS（策略1）和免疫化学粪便试验（FIT）（策略2）两种主要筛查策略识别CRC患者的成本。材料和方法。我们回顾性分析了2004年2月至2010年8月在我们机构的TCS筛查数据库（策略1，n = 15，348）和2008年日本全国CRC筛查调查（策略2，n = 5，267，443）。结果策略1和策略2分别检测到112例和6，838例CRC病例，分别花费2，124，000日元和1，629，000日元。策略1的早期CRC发生率较高。结论.使用TCS作为初级筛选程序的成本较高。然而，这种差异并不过分，考虑到早期CRC检出率的提高，使用TCS作为初级筛查工具可能具有成本效益。
Introduction. In Japan, the cost-effectiveness of total colonoscopy (TCS) for primary screening of colorectal cancer (CRC) is unclear. We compared the cost of identifying a patient with CRC using two primary screening strategies: TCS (strategy 1) and the immunochemical fecal test (FIT) (strategy 2). Materials and Methods. We retrospectively analyzed the TCS screening database at our institution from February 2004 to August 2010 (strategy 1, n = 15,348) and the Japanese nationwide survey of CRC screening in 2008 (strategy 2, n = 5,267,443). Results. 112 and 6,838 CRC cases were detected in strategies 1 and 2, costing 2,124,000 JPY and 1,629,000 JPY, respectively. The rate of earlier-stage CRC was higher in strategy 1. Conclusions. The cost was higher using TCS as a primary screening procedure. However, the difference was not excessive, and considering the increased rate of detecting earlier CRC, the use of TCS as a primary screening tool may be cost-effective.
影响因子：
120.7
作者：
Frazier, AL;Colditz, GA;Kuntz, KM
通讯作者：
Kuntz, KM
影响因子：
158.5
作者：
Mandel, JS;Church, TR;Schuman, LM
通讯作者：
Schuman, LM
影响因子：
158.5
作者：
WINAWER, SJ;ZAUBER, AG;STEWART, ET
通讯作者：
STEWART, ET