GEP-NETs UPDATE: Secreting gastro-enteropancreatic neuroendocrine tumours and biomarkers.

GEP-NETs UPDATE: Secreting gastro-enteropancreatic neuroendocrine tumours and biomarkers.
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GEP-NET 更新:分泌胃肠胰神经内分泌肿瘤和生物标志物。

DOI:
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发表时间:
2016
影响因子:
5.8
通讯作者:
M. Tesselaar
M. Tesselaar
中科院分区:
医学1区
文献类型:
--
作者:
W. Verbeek;C. Korse;M. Tesselaar

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神经内分泌肿瘤(NETs)是一种罕见的肿瘤,每年在人口中的发病率为每10万居民2-5例新病例。NETs在解剖位置、激素产生、临床行为和可能引起的综合征方面变化很大。本文回顾了NETs的许多定位和临床表现,主要关注临床生物标志物及其在医疗实践中的应用。
Neuroendocrine tumours (NETs) are rare tumours with an annual incidence in the population in a range of 2-5 new cases per 100,000 inhabitants. NETs are widely variable in terms of anatomical location, hormone production, clinical behaviour and syndromes they can cause. This article reviews the many localizations and clinical presentations of NETs with a main focus on clinical biomarkers and their use in medical practice.