Segmental measurement of breast cancer-related arm lymphoedema using perometry and bioimpedance spectroscopy
Segmental measurement of breast cancer-related arm lymphoedema using perometry and bioimpedance spectroscopy
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DOI：
10.1007/s00520-010-0896-8
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发表时间：
2011-05-01
影响因子：
3.1
通讯作者：
Kilbreath, Sharon L.
中科院分区：
文献类型：
--
作者：
Czerniec, Sharon A.;Ward, Leigh C.;Kilbreath, Sharon L.
为了确定生物阻抗谱(BIS)是否可以检测到手臂局部淋巴水肿，并将BIS测量结果与等值的肢体体积测量方法进行比较。29名患有轻度至重度上肢淋巴水肿的女性和11名没有淋巴水肿史的女性参加了研究。从腕部尺骨茎突开始，用BIS和PERIMATION对每个手臂进行4×10厘米的节段测量。在有淋巴水肿的女性中，整个手臂和每个手臂节段的平均BIS肢间比率高于可比的周长测量，但对于没有淋巴水肿的女性，BIS测量的平均肢间比率高于可比的周长测量。符合限度分析显示，不同方法之间的平均差异因所测量的节段而不同，从手臂最上端的8.5%到前臂略低于肘部的16.6%不等。对于所有肢体节段，BIS测量有正偏向，随着淋巴水肿严重程度的增加而增加。BIS可用于淋巴水肿的局部测量。由于BIS对细胞外液有特异性，因此对局部淋巴水肿比渗透压法更敏感。
To determine if bioimpedance spectroscopy (BIS) could detect localised lymphoedema of the arm and to compare BIS measurements with equivalent measures of limb volume by perometry.Women with mild to severe upper limb lymphoedema (n = 29) and women with no history of lymphoedema (n = 11) participated. Commencing at the ulnar styloid of the wrist, 4 x 10 cm segment measurements were made of each arm using both BIS and perometry.Average BIS inter-limb ratios for the total arm and each arm segment were higher than comparable perometry measures in women with lymphoedema, but similar to perometry measures for women without lymphoedema. Limits of agreement analysis showed that the mean difference between methods varied according to segment measured, ranging from 8.5% for the uppermost segment of the arm to 16.6% for the forearm segment just below the elbow. For all limb segments, there was a positive bias towards BIS measurements, which increased as lymphoedema severity increased.BIS can be used for localised measurement of lymphoedema. Because it is specific to extracellular fluid, BIS is more sensitive to localised lymphoedema than perometry.