Does the reproductive cycle influence sleep patterns in women with sleep complaints?
Does the reproductive cycle influence sleep patterns in women with sleep complaints?
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DOI：
10.3109/13697130903450147
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发表时间：
2010-12-01
期刊：
影响因子：
2.8
通讯作者：
Tufik, S.
中科院分区：
文献类型：
--
作者：
Hachul, H.;Andersen, M. L.;Tufik, S.
方法对931名因睡眠问题就诊的妇女进行调查。所有受试者在接受多导睡眠图（PSG）记录之前填写了一份睡眠和妇科问卷。结果月经周期不规律的绝经前妇女比月经周期规律的绝经前妇女更容易报告睡眠困难（与入睡和失眠症状有关）（优势比2.1；95%可信区间1.2-3.5）。这些女性表现出轻度睡眠阶段和觉醒阶段的增加。有周期性腿部运动、饱和度低于90%和睡眠效率较高的女性报告了较高比例的经前症状。与没有服用激素避孕药的女性相比，服用激素避孕药的女性打鼾的比例更低，觉醒次数更少，快速眼动潜伏期更长。有潮热的绝经期妇女有更多的不宁腿的抱怨。与未接受激素治疗的患者相比，接受激素治疗的患者清醒时间更短。绝经期妇女更有可能出现呼吸暂停-呼吸不足指数大于5/h。结论睡眠抱怨女性的妇科状况与主观睡眠质量和客观睡眠参数有关。
Methods A total of 931 women who sought clinical assistance because of a sleep complaint were included in the investigation. All subjects filled out a sleep and gynecological questionnaire prior to undergoing a polysomnography (PSG) recording.Results Premenopausal women with an irregular menstrual cycle were more likely to report sleep difficulties (related to falling sleep and insomnia symptoms) than those with a regular cycle (odds ratio 2.1; 95% confidence interval 1.2-3.5). These women showed increased light sleep stages and awakenings. Premenstrual complaints were reported by a higher percentage of women with periodic leg movement, lower time in saturation under 90%, and higher sleep efficiency. A lower percentage of women who took hormonal contraceptives reported snoring, had fewer arousals and longer REM latency compared to those not taking hormonal contraceptives. Menopausal women with hot flushes had more restless leg complaints. Awake time was shorter in hormone therapy users compared with non-users. Women with menopause are more likely to have an apnea-hypoapnea index greater than 5/h.Conclusion The present findings suggest that gynecological status is associated with subjective sleep quality and objective sleep parameters in women with sleep complaints.