Depressive disorders in caregivers of dementia patients: A systematic review
Depressive disorders in caregivers of dementia patients: A systematic review
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DOI：
10.1080/13607860500090078
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发表时间：
2005-07-01
影响因子：
3.4
通讯作者：
Cuijpers, P
中科院分区：
文献类型：
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作者：
Cuijpers, P
虽然抑郁症的症状学已经在痴呆症患者的护理人员中得到了很好的研究，但抑郁症的检查却少得多。我们在主要的文献数据库（Medline, Psychinfo, Dissertation Abstracts）中进行了系统的文献检索，并根据标准化的精神病学诊断访谈评估的诊断标准，纳入了检查痴呆患者护理人员的研究，这些患者报告了重度抑郁症的患病率。10项研究共涉及790名护理人员（样本量：22 - 147）。只有一项研究使用了具有代表性的社区样本。共有176名受试者（22.3%）患有抑郁症（患病率范围为0.15 - 0.32）。在报告男女患病率差异的三项研究中，发现男性的患病率略低于女性。在六项研究中，护理人员与对照组（基本匹配）进行了比较。照顾者患抑郁症的相对风险范围为2.80 - 38.68（所有RR值均显著）。在三个前瞻性研究中，发病率相对较高（0.48）。这项研究清楚地表明，痴呆症患者的护理人员中抑郁症的患病率和发病率都有所增加。显然需要对这一人群进行更多的研究。
Although depressive symptomatology has been well studied in caregivers of patients with dementia, depressive disorders have been examined much less. We conducted a systematic literature search in major bibliographical databases (Medline, Psychinfo, Dissertation Abstracts), and included studies examining caregivers of dementia patients that reported the prevalence of major depressive disorder, according to diagnostic criteria as assessed with a standardized psychiatric diagnostic interview. Ten studies with a total of 790 caregivers were identified ( sample sizes: 22 - 147). In only one of the studies, a representative community sample was used. A total of 176 subjects (22.3%) had a depressive disorder ( prevalence range from 0.15 - 0.32). In the three studies reporting differential prevalence rates for men and women somewhat smaller prevalence rates were found for men than for women. In six studies caregivers were compared to a ( mostly matched) control group. The relative risks of having a depressive disorder in caregivers ranged from 2.80 - 38.68 ( all RR's were significant). In the three prospective studies relatively high incidence rates were found (0.48). This study made it clear that prevalence and incidence of depressive disorders are increased in caregivers of dementia patients. More research is clearly needed in this population.