Strategies for combining and scaling sexual maturity indicators: the Heartfelt Study.
Strategies for combining and scaling sexual maturity indicators: the Heartfelt Study.
复制标题
组合和衡量性成熟指标的策略：衷心研究。
DOI：
10.1080/03014460010019731
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发表时间：
2001
影响因子：
1.7
通讯作者：
Chan,W
中科院分区：
文献类型：
--
作者：
Mueller,WH;Cho,SD;Meininger,JC;Liehr,P;Chan,W
主要目标：确定在青少年健康调查中使用的最佳变量或性成熟变量组合，并探索将五个性成熟阶段重新调整为“虚拟变量”的可能性研究设计：横断面研究对象：384名11-16岁美国青少年的三种族样本方法：性成熟变量是由执业护士通过临床检查获得的生殖器、乳房和阴毛阶段、睾丸大小、月经初潮和月经初潮年龄。对性成熟变量身高和年龄的主因子分析显示，这些变量之间有很高的共性，在28个因素分析中，有27个因素只出现一个因素，生殖器发育阶段（男孩）和乳房发育阶段（女孩）与第一主因子的相关性最高，与年龄和种族无关。对间接反映内分泌功能的“关键变量”进行方差分析表明，某些阶段可以合并。性成熟指数（SMI）：SMI（女孩）=0.998 ×乳房+ 0.900 ×阴毛+ 1.815 ×月经初潮后年龄，SMI（男孩）=1.104 ×生殖器+ 1.328 +阴毛+ 5.997 ×睾丸大小（mL），如果需要的话，将性成熟变量重新划分为“延迟”和“高级”两组得到了适度的支持，因此：（第1、2、3阶段vs第4、5阶段）。
Primary objective: To identify the best variable or combination of sexual maturity variables to use in investigations of adolescent health, and explore possible re-scaling of five-stage sexual maturity stages into 'dummy variables' ('advanced'/'delayed').Research design: Cross-sectional.Subjects: Tri-ethnic sample of 384 US adolescents 11-16 years of age (Heartfelt Study).Methods: Sexual maturity variables are genital, breast and pubic hair stages obtained by clinical examination by nurse practitioners, testes size, menarche and age at menarche.Results: Principal factor analysis of sexual maturity variables, height and age, revealed high commonality among the variables, as no more than a single factor appeared in 27 of 28 factor analyses (by sex and age groups).Genital stage(boys) andbreast stage(girls) were most highly related to the first principal factor independent of age and ethnicity. ANOVA of 'key variables' indirectly reflecting endocrine function suggested that some stages could be combined.ConclusionsA single variable should suffice to describe sexual maturity at the studied ages, or variables could be combined in a (unstandardized) sexual maturity index (SMI): SMI (Girls)=0.998 × BREAST + 0.900 × PUBIC HAIR + 1.815 × YEARS SINCE MENARCHE, SMI (Boys)=1.104 × GENITAL + 1.328 + PUBIC HAIR + 5.997 × TESTES SIZE (mL), There is modest support for re-scaling a sexual maturity variable into `delayed' and 'advanced' groups if needed, thus: (stages 1, 2, 3, vs 4, 5).