Long term results of a randomised prospective study of preservation of the intercostobrachial nerve
Long term results of a randomised prospective study of preservation of the intercostobrachial nerve
复制标题
DOI：
10.1053/ejso.2002.1409
复制
发表时间：
2003-04-01
期刊：
影响因子：
--
通讯作者：
Bundred, NJ
中科院分区：
文献类型：
--
作者：
Freeman, SRM;Washington, SJ;Bundred, NJ
目的：我们之前曾报道过一项随机对照试验，比较肋间臂神经（ICBN）保存与分裂，在3个月的随访中，两组之间的症状没有差异，尽管在手臂上测量到感觉丧失面积减少。为了确定更长时间的随访是否为ICBN保存提供了证据，对试验患者进行了术后3年（32-38个月）的随访。方法：对原组120例患者中的73例患者的感觉症状和缺陷、疼痛、肩部运动、臂围和神经瘤的存在进行记录。结果：两组生存率及腋窝复发率无差异。两组之间唯一不同的症状是对“不同感觉”的主观评估（P = 0.006）。在其他感觉症状、疼痛、肩部运动、手臂围度或神经瘤的存在方面没有观察到显著差异。与保留神经的女性相比，牺牲神经的女性感觉缺损面积更大（P = 0.009）。结论：保留肋间臂神经不影响患者的生存。它能显著改善患者的感觉缺陷，并适度改善长期症状。(C) 2002 Elsevier Science Ltd.版权所有。
Aims: We have previously reported in a randomised controlled trial comparing intercostobrachial nerve (ICBN) preservation with division that no difference in symptoms was seen between the groups at 3 months follow-up although a reduced area of sensory loss was measured on the arm. To determine if longer follow-up provides evidence for ICBN preservation, follow-up of patients in the trial at 3 years (range 32-38 months) postoperatively was performed.Methods: Sensory symptoms and deficits, pain, shoulder movements, arm circumference and the presence of neuromas were documented in 73 patients from the original group of 120.Results: No difference in survival or axillary recurrence was observed. The only symptom which differed between the two groups was a subjective assessment of 'different sensation' (P = 0.006). No significant difference was observed in other sensory symptoms, pain, shoulder movement, arm circumference or presence of neuromas. A larger area of sensory deficit was measured in women with sacrificed nerves compared to preserved (P = 0.009).Conclusion: Preservation of the intercostobrachial nerve does not affect patient survival. It improves patient sensory deficit significantly and modestly improves long-term symptoms. (C) 2002 Elsevier Science Ltd. All rights reserved.