Effect of Three Diets (Low-FODMAP, Gluten-free and Balanced) on Irritable Bowel Syndrome Symptoms and Health-Related Quality of Life
Effect of Three Diets (Low-FODMAP, Gluten-free and Balanced) on Irritable Bowel Syndrome Symptoms and Health-Related Quality of Life
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DOI：
10.3390/nu11071566
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发表时间：
2019-07-01
期刊：
影响因子：
5.9
通讯作者：
Usai, Paolo
中科院分区：
文献类型：
--
作者：
Paduano, Danilo;Cingolani, Arianna;Usai, Paolo
几项研究报告了低发酵性碳水化合物（可发酵寡糖、二糖、单糖和多元醇（FODMAPs））饮食对肠易激综合征（IBS）的一些疗效。没有证据表明其在改善IBS患者生活质量（QoL）方面优于无麸质和平衡饮食。本研究的目的是评估不同的饮食是否可以改善IBS的生活质量。根据罗马IV标准，入选42例IBS患者。低FODMAP，无麸质和平衡的饮食，建议在同一序列的每一个病人。每种饮食持续4周。在每次饮食开始和结束时，应用布里斯托粪便量表、腹胀和腹痛视觉疼痛量表（VAS）以及SF 12健康相关生活质量问卷。42名患者中有28名完成了所有三种饮食。所有三种饮食都减轻了症状严重程度（p < 0.01），腹胀（p < 0.01）和腹痛（p < 0.01），并改善了生活质量（p < 0.05）; 3%的患者表示偏好低FODMAP饮食，11%的患者表示偏好无麸质饮食，86%的患者表示偏好平衡饮食（p < 0.01）。均衡饮食改善了QoL和VAS疼痛，提供了足够量的FODMP，更受患者欢迎。因此，均衡饮食可推荐给肠易激综合征患者。
Several studies have reported some efficacy of diets low in fermentable carbohydrates (Fermentable Oligo-, Di-, Monosaccharides and Polyols (FODMAPs)) in Irritable Bowel Syndrome (IBS). There is no evidence of its superiority compared to gluten-free and balanced diets in improving IBS patients' quality of life (QoL). The aim of this study is to assess whether different diets can improve QoL in IBS. Forty-two patients with IBS, according to Rome IV criteria, were enrolled. Low-FODMAP, gluten-free and balanced diets were proposed to each patient in the same succession. Each diet was followed for 4 weeks. The Bristol Stool Scale, the Visual Analogue Scale (VAS) for bloating and abdominal pain, and the SF12 questionnaire for health-related quality of life were applied at the beginning and at the end of each diet. Twenty-eight of the forty-two patients completed all the three diets. All the three diets reduced symptom severity (p < 0.01), bloating (p < 0.01) and abdominal pain (p < 0.01), and improved quality of life (p < 0.05); 3% of patients expressed a preference for the low-FODMAP diet, 11% for the gluten-free and 86% for the balanced diet (p < 0.01). The balanced diet improves QoL and VAS pain, provides an adequate quantity of FODMAPs and is more appreciated by patients. For these reasons, the balanced diet could be recommended to patients with irritable bowel syndrome.