Fenofibrate therapy ameliorates fasting and postprandial lipoproteinemia, oxidative stress, and the inflammatory response in subjects with hypertriglyceridemia and the metabolic syndrome

Fenofibrate therapy ameliorates fasting and postprandial lipoproteinemia, oxidative stress, and the inflammatory response in subjects with hypertriglyceridemia and the metabolic syndrome
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DOI:
10.2337/dc07-0015
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发表时间:
2007-08-01
期刊:
影响因子:
16.2
通讯作者:
Rademaker, Alfred W.
Rademaker, Alfred W.
中科院分区:
医学1区
文献类型:
--
作者:
Rosenson, Robert S.;Wolff, David A.;Rademaker, Alfred W.

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目的:本研究的目的是确定非诺贝特(160 mg/天)对高脂血症和代谢综合征受试者空腹和餐后脂蛋白、氧化脂肪酸和炎症介质的影响。研究设计和方法-59例空腹高血脂症受试者(>= 1. 7和
OBJECTIVE- The aim of this study was to determine the effects of fenofibrate (160 mg/day) on fasting and postprandial lipoproteins, oxidized fatty acids, and inflammatory mediators in subjects with hypertriglyceridemia and the metabolic syndrome. RESEARCH DESIGN AND METHODS - Fifty-nine subjects with fasting hypertriglyceridemia (>= 1. 7 and