Neurobehavioral development in children with potential exposure to pesticides
Neurobehavioral development in children with potential exposure to pesticides
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DOI：
10.1097/01.ede.0000259983.55716.bb
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发表时间：
2007-05-01
期刊：
影响因子：
5.4
通讯作者：
Harlow, Sioban D.
中科院分区：
文献类型：
--
作者：
Handal, Alexis J.;Lozoff, Betsy;Harlow, Sioban D.
背景资料：儿童可能比成人更容易接触农药，因为他们的生理发育迅速，独特的行为模式以及与物理环境的相互作用。在厄瓜多尔进行的初步研究探讨家庭和环境的农药暴露和neurobiological development.Methods的风险因素之间的关联：我们收集了6个月以上的数据，在农村高原地区的卡扬贝，厄瓜多尔（2003-2004年）。年龄24-61个月的儿童居住在3个社区进行了评估与年龄和阶段问卷和视觉运动整合测试。我们收集了有关产妇健康和工作特征、家庭和社区环境以及儿童特征的信息。获得生长测量和血红蛋白手指采血试验。多元线性回归分析carried.Results：目前的母亲在花卉业的就业与更好的发展分数。长时间的户外运动与较低的粗运动和精细运动以及解决问题的能力有关。玩灌溉水的孩子在精细运动技能上得分较低（下降8%; 95%置信区间= -9.31至-0.53），解决问题的能力（下降7%; -8.40至-0.39），视觉运动整合测试评分结论：这些结果表明，接触农药的某些环境风险因素可能会影响儿童的发育，特别是与灌溉水的接触。然而，这些风险因素与社会特征之间的关系是复杂的，因为公司农业可能会通过农药接触和环境污染增加风险，同时通过提供医疗保健、相对较高的工资和日托选择间接促进健康发展。
Background: Children may be at higher risk than adults from pesticide exposure, due to their rapidly developing physiology, unique behavioral patterns, and interactions with the physical environment. This preliminary study conducted in Ecuador examines the association between household and environmental risk factors for pesticide exposure and neurobehavioral development.Methods: We collected data over 6 months in the rural highland region of Cayambe, Ecuador (2003-2004). Children age 24-61 months residing in 3 communities were assessed with the Ages and Stages Questionnaire and the Visual Motor Integration Test. We gathered information on maternal health and work characteristics, the home and community environment, and child characteristics. Growth measurements and a hemoglobin finger-prick blood test were obtained. Multiple linear regression analyses were conducted.Results: Current maternal employment in the flower industry was associated with better developmental scores. Longer hours playing outdoors were associated with lower gross and fine motor and problem solving skills. Children who played with irrigation water scored lower on fine motor skills (8% decrease; 95% confidence interval = -9.31 to -0.53), problem-solving skills (7% decrease; -8.40 to -0.39), and Visual Motor Integration test scores (3% decrease; -12.00 to 1.08).Conclusions: These results suggest that certain environmental risk factors for exposure to pesticides may affect child development, with contact with irrigation water of particular concern. However, the relationships between these risk factors and social characteristics are complex, as corporate agriculture may increase risk through pesticide exposure and environmental contamination, while indirectly promoting healthy development by providing health care, relatively higher salaries, and daycare options.