SICCA COMPLEX IN LIVER DISEASE
SICCA COMPLEX IN LIVER DISEASE
复制标题
DOI：
10.1136/bmj.4.5731.340
复制
发表时间：
1970-01-01
影响因子：
--
通讯作者：
TAYLOR, E
中科院分区：
文献类型：
--
作者：
GOLDING, PL;BOWN, R;TAYLOR, E
研究了63例肝病患者是否存在干燥综合征的成分。在42%的慢性活动性肝炎患者、72%的原发性胆汁性肝硬化患者和38%的隐源性肝硬化患者中检测到“干燥综合征”（即没有关节炎的患者）。1例慢性活动性肝炎和1例原发性胆汁性肝硬化患者发生类风湿性关节炎。在7例酒精性肝硬化患者中未检测到干燥综合征的证据。这表明，干燥综合征和自身免疫性肝病可能是一个系统性疾病的一部分，其中免疫机制在发病机制有关。
Sixty-three patients with liver disease were studied for the presence of the components of Sjögren's syndrome. The “sicca complex” (that is, patients without arthritis) was detected in 42% of patients with active chronic hepatitis, 72% with primary biliary cirrhosis, and 38% with cryptogenic cirrhosis. One patient with active chronic hepatitis and one with primary biliary cirrhosis had rheumatoid arthritis. No evidence of Sjögren's syndrome was detected in seven patients with alcoholic cirrhosis. It is suggested that the sicca complex and autoimmune liver disease may be part of a systemic disorder in which immunological mechanisms are concerned in the pathogenesis.