Sulforaphane Attenuates Glycoprotein VI-mediated Platelet Mitochondrial Dysfunction through Up-regulating cAMP/PKA Signaling Pathway in vitro and in vivo
Sulforaphane Attenuates Glycoprotein VI-mediated Platelet Mitochondrial Dysfunction through Up-regulating cAMP/PKA Signaling Pathway in vitro and in vivo
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DOI:
10.1039/d2fo03958c
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发表时间:
2023
期刊:
影响因子:
6.1
通讯作者:
Fuli Ya
中科院分区:
文献类型:
--
作者:
Xinyu Zhou;Xinhui Huang;Chunting Wu;Yongjie Ma;Weiqi Li;Jinqiu Hu;Rong Li;Fuli Ya
Platelet mitochondrial dysfunction is crucial for platelet activation, atherosclerosis and thrombosis. Sulforaphane (SFN) is a dietary isothiocyanate enriched in cruciferous vegetables and possesses multiple health benefits including cardiovascular protection. This...