Transcatheter Arterial Embolization of Experimental Hepatic Tumours in the Rat
Transcatheter Arterial Embolization of Experimental Hepatic Tumours in the Rat
复制标题
大鼠实验性肝肿瘤的经导管动脉栓塞
DOI：
10.1177/028418517902000304
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发表时间：
1979
期刊：
影响因子：
--
通讯作者：
H. Sjögren
中科院分区：
文献类型：
--
作者：
L. Stigsson;L. Ekelund;N. Jonsson;H. Sjögren
在一组实验性肝肿瘤大鼠中使用Spongostan（99.3%明胶-类似于明胶海绵）进行经导管动脉栓塞后，将血管造影和显微镜检查结果与一组未栓塞肝肿瘤大鼠进行比较。肝动脉部分再通已在2至6天后证实。栓塞后肿瘤血管形成减少，少数动物的肿瘤甚至缩小。显微镜检查显示，栓塞肿瘤的大尺寸的肿瘤坏死的程度显着更大。在栓塞大鼠中发现不同程度的正常肝组织坏死，而在大多数非栓塞动物的肝脏中没有明显的缺血性损伤。
After transcatheter arterial embolization with Spongostan (99.3% gelatin-similar to gelfoam) in a group of rats with experimental hepatic tumours, the angiographic and microscopic findings were compared with those in a group of rats with non-embolized liver tumours. Partial recanalization of the hepatic artery was demonstrated already after 2 to 6 days. Reduced vascularization of tumours could be demonstrated after embolization and in a few animals even decrease in tumour size. Microscopy revealed a significantly greater extent of tumour necrosis in embolized tumours of large size. Necrosis of normal liver tissue was found to a varying degree in the embolized rats, while no ischemic injury was evident in livers of most non-embolized animals.