Prospective evaluation of automated follicle monitoring in 58 in vitro fertilization cycles: follicular volume as a new indicator of oocyte maturity
Prospective evaluation of automated follicle monitoring in 58 in vitro fertilization cycles: follicular volume as a new indicator of oocyte maturity
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DOI：
10.1016/j.fertnstert.2009.02.058
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发表时间：
2010-01-15
影响因子：
6.7
通讯作者：
Palumbo, Angela
中科院分区：
文献类型：
--
作者：
Rodrigue-Fuentes, Adela;Hernandez, Jairo;Palumbo, Angela
目的：评估SonoAVC在IVF程序中的实际应用，并根据卵泡体积建立hCG给药的新标准。设计：前瞻性临床研究。设置：私人IVF中心。患者：58名接受IVF的不孕症妇女。干预：hCG给药当天的二维（2D）和三维（3D）扫描。主要结果测量：图像质量、二维和三维超声检查获得的卵泡平均直径、卵泡体积、获卵数、成熟卵数、每次检查所需时间。结果：约60%的患者具有良好的图像质量，并且可以通过随后应用SonoAVC软件的3D扫描进行监测。当图像质量良好时，在62%的情况下，通过自动模式获得的测量结果与手动获得的测量结果相当。自动化监控比传统的手动监控快得多。卵泡测量体积>= 0.6 cc的hCG管理的一天与成熟卵母细胞的发现在egg retrieval. Conclusions的时间：SonoAVC允许可靠的评估刺激卵巢，并可能帮助我们建立新的标准，根据卵泡体积估计，而不是卵泡大小的hCG管理的时间。需要改进软件以提高患者的普遍使用。（Fertil Steril（R）2010-793：616-20.（C）2010年由美国生殖医学学会。
Objectives: To assess the practical use of SonoAVC in an IVF program, and to establish new criteria for hCG administration based on follicular volume.Design: Prospective clinical study.Setting: Private IVF Center.Patient(s): Fifty-eight women with infertility undergoing IVF.Intervention(s): Two dimensional (2D) and three dimensional (3D) scanning on the day of hCG administration.Main Outcome Measure(s): image quality, mean follicular diameter obtained by 2D and 3D sonography, follicular volume, number of oocytes retrieved, number of mature oocytes, time needed for each examination.Result(s): Approximately 60% of the patients included in this study had good image quality and could be monitored by 3D scans with subsequent application of the SonoAVC software. When image quality is good, measurements obtained by the automated mode are comparable to those obtained manually in 62% of cases. Automated monitoring is significantly quicker than conventional manual monitoring. Follicles with a measured volume >= 0.6 cc on the day of hCG administration are associated with the finding of mature oocytes at the time of egg retrieval.Conclusion(s): SonoAVC allows reliable evaluation of stimulated ovaries, and may help us establish new criteria for timing hCG administration based on follicular volume estimation rather than follicular size. Software improvements are needed to improve universal patient use. (Fertil Steril(R) 2010-793:616-20. (C)2010 by American Society for Reproductive Medicine.)