The myoblast autologous grafting in ischemic cardiomyopathy (MAGIC) trial -: First randomized placebo-controlled study of myoblast transplantation
The myoblast autologous grafting in ischemic cardiomyopathy (MAGIC) trial -: First randomized placebo-controlled study of myoblast transplantation
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DOI：
10.1161/circulationaha.107.734103
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发表时间：
2008-03-04
期刊：
影响因子：
37.8
通讯作者：
Hagege, Albert A.
中科院分区：
文献类型：
--
作者：
Menasche, Philippe;Alfieri, Ottavio;Hagege, Albert A.
背景一期临床研究已经证明了在梗死后疤痕中植入自体骨骼成肌细胞的可行性。然而，他们未能确定该手术是否在功能上有效且会导致心律失常。 方法和结果 - 这项多中心、随机、安慰剂对照、双盲研究纳入了左心室 (LV) 功能障碍（射血分数）患者
Background-Phase I clinical studies have demonstrated the feasibility of implanting autologous skeletal myoblasts in postinfarction scars. However, they have failed to determine whether this procedure was functionally effective and arrhythmogenic.Methods and Results-This multicenter, randomized, placebo-controlled, double-blind study included patients with left ventricular (LV) dysfunction (ejection fraction