Mechanisms of chromosome behaviour during mitosis.
Mechanisms of chromosome behaviour during mitosis.
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DOI:
10.1038/nrm2832
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发表时间:
2010-02
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影响因子:
--
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中科院分区:
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--
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For over a century, scientists have strived to understand the mechanisms that govern the accurate segregation of chromosomes during mitosis. The most intriguing feature of this process, which is particularly prominent in higher eukaryotes, is the complex behaviour exhibited by the chromosomes. This behaviour is based on specific and highly regulated interactions between the chromosomes and spindle microtubules. Recent discoveries, enabled by high-resolution imaging combined with the various genetic, molecular, cell biological and chemical tools, support the idea that establishing and controlling the dynamic interaction between chromosomes and microtubules is a major factor in genomic fidelity.
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影响因子:
21.3
作者:
Bakhoum, Samuel F.;Thompson, Sarah L.;Manning, Amity L.;Compton, Duane A.
通讯作者:
Compton, Duane A.
影响因子:
4
作者:
Cimini, D;Moree, B;Salmon, ED
通讯作者:
Salmon, ED
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通讯作者:
Kapoor, Tarun M.
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Brunet, S;Maria, AS;Maro, B
通讯作者:
Maro, B
影响因子:
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作者:
DeLuca, JG;Howell, BJ;Salmon, ED
通讯作者:
Salmon, ED