Remineralization of in vitro dental caries assessed with polarization-sensitive optical coherence tomography
Remineralization of in vitro dental caries assessed with polarization-sensitive optical coherence tomography
复制标题
DOI：
10.1117/1.2161192
复制
发表时间：
2006-01-01
影响因子：
3.5
通讯作者：
Fried, D
中科院分区：
文献类型：
--
作者：
Jones, RS;Darling, CL;Fried, D
偏振敏感光学相干断层扫描（PS-OCT）是潜在的有用的成像非手术的牙釉质脱矿。本研究使用在1310 nm下工作的全光纤PS-OCT系统对脱矿和氟化物增强的矿化人工病变进行成像。PS-OCT图像的病变之前和之后再矿化进行了比较，相对矿物质损失Δ Z（%体积x μ m），从高分辨率数字显微放射照相（DM），和化学成分的变化，红外光谱。严重的早期人工龋显示出显着增加后，矿化后的牙轴积分反射率。切片后的样品，DM表明，与新的矿物和损伤表面区域显示出显着的矿物体积恢复的病变矿化。PS-OCT和DM均未显示病变深度的重大变化。对于不太严重的人工龋，光轴图像解决了散射和去极化的外生长层后，去极化。该外层的矿物体积接近于健康釉质的矿物体积，光谱分析表明该层是磷灰石的高度结晶相，没有增加健康釉质溶解度的碳酸盐替代物。本研究确定PS-OCT可以成像轻度和重度早期人工离体龋的氟化物增强再矿化的效果。(c)2006年，由光学仪器工程师协会（Society of Photo-Optical Instrumentation Engineers）主办。
Polarization-sensitive optical coherence tomography (PS-OCT) is potentially useful for imaging the nonsurgical remineralization of dental enamel. This study uses an all-fiber-based PS-OCT system operating at 1310 nm to image demineralized and fluoride-enhanced remineralized artificial lesions. PS-OCT images of lesions before and after remineralization are compared with the relative mineral loss Delta Z (% vol x mu m), obtained from high resolution digital microradiography (DM), and chemical composition changes by infrared spectroscopy. Severe early artificial caries show a significant increase in perpendicular-axis integrated reflectivity after remineralization. After sectioning the samples, DM demonstrates that the lesions remineralized with new mineral and the lesion surface zone show significant restoration of mineral volume. PS-OCT and DM both do not show a major change in lesion depth. For less severe artificial caries, the perpendicular-axis image resolves the scattering and depolarization of an outer growth layer after remineralization. This outer layer has a mineral volume close to that of sound enamel, and spectroscopic analysis indicates that the layer is a highly crystalline phase of apatite, without carbonate substitutions that increase the solubility of sound enamel. This study determines that PS-OCT can image the effects of fluoride-enhanced remineralization of mild and severe early artificial in vitro caries. (c) 2006 Society of Photo-Optical Instrumentation Engineers.