FOREBRAIN LESIONS DISRUPT DEVELOPMENT BUT NOT MAINTENANCE OF SONG IN PASSERINE BIRDS
FOREBRAIN LESIONS DISRUPT DEVELOPMENT BUT NOT MAINTENANCE OF SONG IN PASSERINE BIRDS
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DOI：
10.1126/science.6719123
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发表时间：
1984-01-01
期刊：
影响因子：
56.9
通讯作者：
ARNOLD, AP
中科院分区：
文献类型：
--
作者：
BOTTJER, SW;MIESNER, EA;ARNOLD, AP
前新纹状体的大细胞核是雀形目鸟类的前脑核，它积累睾丸激素，并与其他控制成年鸟类鸣叫的远端脑核建立单突触连接。雄斑胸草雀的大细胞核损伤破坏了幼斑胸草雀的鸣叫发育，但不影响成年斑胸草雀维持稳定的鸣叫模式。这些结果代表了一个实例，即在学习行为发展的有限阶段，一个离散的大脑区域的损伤会导致永久性损伤。由于大细胞核细胞积累雄激素，鸣叫学习可能是由激素介导的。
The magnocellular nucleus of the anterior neostriatum is a forebrain nucleus of passerine birds that accumulates testosterone and makes monosynaptic connections with other telencephalic nuclei that control song production in adult birds. Lesions in the magnocellular nucleus disrupted song development in juvenile male zebra finches but did not affect maintenance of stable song patterns by adult birds. These results represent an instance in which lesions of a discrete brain region during only a restricted phase in the development of a learned behavior cause permanent impairment. Because cells of the magnocellular nucleus accumulate androgens, song learning may be mediated by hormones.