A comparative study of aortic wall stress using finite element analysis for ruptured and non-ruptured abdominal aortic aneurysms
A comparative study of aortic wall stress using finite element analysis for ruptured and non-ruptured abdominal aortic aneurysms
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DOI：
10.1016/j.ejvs.2004.03.029
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发表时间：
2004-08-01
影响因子：
5.7
通讯作者：
McCollum, PT
中科院分区：
文献类型：
--
作者：
Venkatasubramaniam, AK;Fagan, MJ;McCollum, PT
背景无症状腹主动脉瘤（AAA）修复的决定目前仅基于直径（大于或等于5.5 cm）。然而，小于5.5 cm的动脉瘤会破裂，而一些动脉瘤达到大于5.5 cm时不会破裂。因此，需要预测破裂的风险，在个别患者的基础上是重要的。本研究旨在计算和比较破裂和非破裂AAA的壁应力。AAA的3D几何形状来自27例患者（12例破裂和15例非破裂）的CT扫描。AAA的几何形状，收缩压和文献推导的材料属性，被用来计算壁应力的单个AAA使用有限元分析。破裂AAA的峰值壁应力（平均1.02 MPa）显著高于未破裂AAA（平均0.62 MPa）。在CT扫描上可识别破裂部位的患者中，壁应力峰值面积与破裂部位相关。峰值壁应力可以通过常规CT扫描计算，并且可能是比AAA直径更好的破裂风险预测因子。
Background. The decision to repair an asymptomatic abdominal aortic aneurysm (AAA) is currently based on diameter (greater than or equal to 5.5 cm) alone. However, aneurysms less than 5.5 cm do rupture while some reach greater than 5.5 cm without rupturing. Hence the need to predict the risk of rupture on an individual patient basis is important. This study aims to calculate and compare wall stress in ruptured and non-ruptured AAA.Methods. The 3D geometries of AAA were derived from CT scans of 27 patients (12 ruptured and 15 non-ruptured). AAA geometry, systolic blood pressure and literature derived material properties, were utilised to calculate wall stress for individual AAA using finite element analysis.Results. Peak wall stress was significantly higher in the ruptured AAA (mean 1.02 MPa) than the non-ruptured AAA (mean 0.62 MPa). In patients with an identifiable site of rupture on CT scan, the area of peak wall stress correlated with rupture site.Conclusions. Peak wall stress can be calculated from routinely performed CT scans and may be a better predictor of risk of rupture than AAA diameter on an individual patient basis.