MGO on the go: Multiscale genome symposium - annual biophysical society meeting 2021.
MGO on the go: Multiscale genome symposium - annual biophysical society meeting 2021.
复制标题
移动中的 MGO：多尺度基因组研讨会 - 2021 年生物物理学会年度会议。
DOI：
10.1007/s12551-021-00799-5
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发表时间：
2021
影响因子：
--
通讯作者：
Bishop,ThomasC
中科院分区：
文献类型：
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作者：
Schlick,Tamar;Bishop,ThomasC
在 2021 年生物物理学会 (BPS) 虚拟年会上，我们很高兴为新成立的小组——多尺度基因组组织 (MGO) 举办了第一次小型研讨会。我们小组的这个想法是在 2019 年 3 月/4 月在法国 Les Houches 风景如画的法国阿尔卑斯山风景如画的 Ecole des Physiques 举行的关于染色质多尺度建模的 BPS 主题会议上提出的（Schlick 2020）。可能受到勃朗峰背景的影响，激励我们胸怀广阔、雄心勃勃，我们的梦想——将生物学家、化学家、物理学家和数学家聚集在一起讨论和开展合作，通过新的概念方法和视角推进染色质结构、动力学、功能和应用领域——现在已经成为现实。我们特别兴奋地将实验学家和理论家/建模者聚集在一起，并强调有关基因组（从碱基到染色体）复杂的多尺度特征和特性的技术和想法之间的相互作用。需要这种在许多空间和时间尺度上的多尺度模型和实验策略来解决染色体折叠问题和基因表达的表观基因组调控的所有组成部分。我们于 2 月 22 日举行的小型研讨会有来自三大洲和多个时区的八位演讲者。尽管存在一些技术故障，我们还是进行了精彩的讨论和聊天，清楚地展示了社区成员如何
At the virtual 2021 Biophysical Society (BPS) Annual meeting, we were happy to hold the first minisymposium of our newly formed subgroup, Multiscale Genome Organization (MGO). This idea for our subgroup emerged during the March/April 2019 BPS Thematic Meeting on chromatin multiscale modeling held at the picturesque Ecole des Physiques in the French Alps at Les Houches, France (Schlick 2020). Likely influenced by Mont Blanc in the background, inspiring us to be broad and ambitious, our dream—to bring together biologists, chemists, physicists, and mathematicians to discuss and launch collaborations and advance the field of chromatin structure, dynamics, function and applications through new conceptual approaches and perspectives—is now a reality. We are particularly excited about bringing together experimentalists and theoreticians/modelers and emphasizing the interplay between techniques and ideas concerning the complex multiscale features and properties of genomes, from bases to chromosomes. Such multiscale models and experimental strategies on many spatial and temporal scales are needed to address all components of the chromosome folding problem and the epigenomic regulation of gene expression. Our minisymposium on February 22nd featured eight speakers spanning three continents and many time zones. Despite some technical glitches, we held great discussion and chats, clearly demonstrating how community members