Enhancing the quality of studies using transcranial magnetic and electrical stimulation with a new computer-controlled system

Enhancing the quality of studies using transcranial magnetic and electrical stimulation with a new computer-controlled system
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DOI:
10.1016/s0165-0270(00)00284-3
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发表时间:
2000-10-15
影响因子:
3
通讯作者:
Cohen, LG
Cohen, LG
中科院分区:
医学4区
文献类型:
--
作者:
Kaelin-Lang, A;Cohen, LG

文献摘要

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人脑的经颅磁刺激(TMS)和电刺激(TES)已成为神经生理学和神经心理学研究的有用工具。在这里,我们描述了一个集成的系统,它允许对神经生理学和神经心理学的TMS和TES程序进行实验控制、数据记录和分析(包括运动阈值、招募曲线、皮质内抑制和使用成对脉冲的促进)。该系统采用了一块多功能输入输出板和一套用LabVIEW图形化编程语言编写的虚拟仪器。它还包括使用Boltzmann Sigmoid函数对招募曲线进行在线曲线拟合,以及监测目标肌肉的预神经支配级别。可以很容易地添加用于神经心理刺激呈现或更快重复刺激的模块。该系统在用户友好和统一的环境中产生更准确的数据记录和分析。(C)2000年,爱思唯尔科学公司出版。
Transcranial magnetic (TMS) and electrical (TES) stimulation of the human brain have become useful tools in neurophysiological and neuropsychological research. Here we describe an integrated system that allows experimental control, data recording and analysis of neurophysiological and neuropsychological TMS and TES procedures (including motor thresholds, recruitment curves, intracortical inhibition and facilitation with paired pulses). The system uses a multifunction input/output board and a set of virtual instruments (VI) programmed with the Labview graphical programming language. It also includes online curve fitting of recruitment curves using the Boltzmann sigmoid function and monitoring of the preinnervation grade of the target muscle. Modules for neuropsychological stimulus presentation or faster repetitive stimulation can be easily added. This system yields more accurate data recording and analysis in a user friendly and unified environment. (C) 2000 Published by Elsevier Science B.V.