Dose-response relationship in the yield of radiation-induced free radicals in amino acids.

Dose-response relationship in the yield of radiation-induced free radicals in amino acids.
复制标题

氨基酸中辐射诱导的自由基产量的剂量-反应关系。

DOI:
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发表时间:
1963
影响因子:
3.5
通讯作者:
J. Simmons
J. Simmons
中科院分区:
工程技术2区
文献类型:
--
作者:
J. Rotblat;J. Simmons

文献摘要

被引文献

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用电子自旋共振技术研究了甘氨酸、丙氨酸、缬氨酸、天冬氨酸和谷氨酸中长寿命自由基的产生。用14.3 MeV电子作为辐射源,在很高的剂量率下,测量了自由基产额与剂量的关系。在所有情况下,在高剂量下(在兆拉范围内)都观察到饱和。用指数函数分析了产额-剂量曲线,并提出了一些可能的解释。计算了单位剂量产额的绝对值和饱和值,并讨论了这些值可能的误差来源。
The electron spin resonance technique has been used to study the production of long-lived radicals in glycine, alanine, valine, aspartic acid and glutamic acid. The yield of radicals as a function of dose was measured, using as a source of radiation 14·3 MeV electrons at a very high dose rate. In all cases saturation was observed at high doses (in the megarad range). The yield vs. dose curves were analysed in terms of exponential functions and some possible explanations put forward. Absolute values of the yield per unit dose, as well as the saturation values, were calculated, and possible sources of error in these values were discussed.