The origin of interspersed repeats in the human genome
The origin of interspersed repeats in the human genome
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DOI：
10.1016/s0959-437x(96)80030-x
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发表时间：
1996-12-01
影响因子：
4
通讯作者：
Smit, AFA
中科院分区：
文献类型：
--
作者：
Smit, AFA
超过三分之一的人类基因组由散布的重复序列组成，这些序列主要是转座元件的简并拷贝。在过去的一年里，许多转座因子的身份被揭示。新兴的概念是，只有三种扩增机制负责绝大多数散布重复，并且每个自主元件都有许多依赖的非自主序列共同扩增。
Over a third of the human genome consists of interspersed repetitive sequences which are primarily degenerate copies of transposable elements. In the past year, the identities of many of these transposable elements were revealed. The emerging concept is that only three mechanisms of amplification are responsible for the vast majority of interspersed repeats and that with each autonomous element a number of dependent non-autonomous sequences have co-amplified.