Fishing for the secrets of vertebrate evolution in threespine sticklebacks.
Fishing for the secrets of vertebrate evolution in threespine sticklebacks.
复制标题
探寻三刺棘鱼脊椎动物进化的秘密。
DOI：
10.1002/dvdy.20564
复制
发表时间：
2005
期刊：
影响因子：
--
通讯作者：
Peichel,CatherineL
中科院分区：
文献类型：
--
作者：
Peichel,CatherineL
三棘鱼（Gasterosteus aculeatus）作为一种新的模式遗传系统正在迅速崛起，以研究进化和发育的界面问题。这种小型硬骨鱼的相对快速和最近的多样化，加上这种鱼的遗传和基因组工具的发展，提供了一个前所未有的机会，以确定自然种群的脊椎动物形态变异的遗传和分子基础。最近，棘鱼两种不同适应性形态特征的基因已被确定。这项工作回答了进化和发育领域中的四个长期存在的问题：（1）自然种群中有多少基因构成形态变异的基础？(2)在自然种群中，构成形态变异的基因是什么？(3)编码或调控突变是形态进化的基础吗？(4)平行形态进化的分子和遗传基础是什么？由于棘鱼种群也显示自然变异的形态，生活史，生理和行为，扩展的方法来确定棘鱼的形态变异的遗传基础，其他表型肯定会产生进一步的重要见解的遗传和发展的基础上的多样性在自然种群。发展动力学234：815-823，2005年。© 2005 Wiley利斯公司
The threespine stickleback (Gasterosteus aculeatus) is rapidly emerging as a new model genetic system to study questions at the interface of evolution and development. The relatively rapid and recent diversification of this small teleost fish, combined with the development of genetic and genomic tools for this fish, provides an unprecedented opportunity to identify the genetic and molecular basis of morphological variation in natural populations of vertebrates. Recently, the genes underlying two different adaptive morphological traits in stickleback have been identified. This work has provided answers to four longstanding questions in the field of evolution and development: (1) How many genes underlie morphological variation in natural populations? (2) What are the genes that underlie morphological variation in natural populations? (3) Do coding or regulatory mutations underlie morphological evolution? (4) What is the molecular and genetic basis of parallel morphological evolution? Because stickleback populations also display natural variation in morphology, life history, physiology, and behavior, extending the approaches used to identify the genetic basis of morphological variation in sticklebacks to other phenotypes is sure to yield further important insights into the genetic and developmental basis of diversity in natural populations. Developmental Dynamics 234:815–823, 2005. © 2005 Wiley‐Liss, Inc.