Comparative study of a novel portable indirect calorimeter to a reference breath-by-breath instrument and its use in telemedicine settings.
Comparative study of a novel portable indirect calorimeter to a reference breath-by-breath instrument and its use in telemedicine settings.
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新型便携式间接热量计与参考呼吸仪器的比较研究及其在远程医疗环境中的使用。
DOI：
10.1016/j.clnesp.2021.09.731
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发表时间：
2021-12
影响因子：
3
通讯作者：
Forzani E
中科院分区：
文献类型：
--
作者：
Mora SJ;Sprowls M;Tipparaju VV;Wheatley-Guy CM;Kulick D;Johnson B;Xiaojun X;Forzani E
静息能量消耗（REE）定量描述静息状态下用于支持身体功能（例如呼吸、血液循环等）的卡路里。 REE 评估对于成功的体重管理和了解代谢健康至关重要。 REE 通常通过间接量热法测定。目前的生物医学间接量热技术利用耗氧量 (VO2) 和二氧化碳产生量 (VCO2) 速率（通常以代谢车的形式）进行评估，体积庞大，需要现场校准和/或经过培训的专业人员来操作。我们推出了一种经 FDA 批准的新型可穿戴医疗设备，以准确、便携式和用户友好的格式确定 REE，可供临床环境中的健康专业人员和患者在家中使用。此前，我们报道了通过气体交换测量黄金标准道格拉斯袋法对 Breezing Med（也称为 Breezing Pro™）进行的验证，并且两种方法在测定 REE、VO2 和 VCO2 速率方面发现了极好的一致性。现在，我们介绍 Breezing Med 针对 Medical Graphics (MGC) CPX Ultima™ 的验证，CPX Ultima™ 是 FDA 510k 批准的代谢推车，其原理基于逐次呼吸分析。此外，我们还推出 Breezing Med 作为非专业人士在家中日常测量代谢率的工具。 A) 验证研究是通过使用 Breezing Med 和 MGC Ultima CPX™（10 分钟测试）在休息条件下对 20 名健康参与者进行平行测量来执行的。 B) Breezing Med 测量由 6 名受试者在 30 天的 COVID-19 居家令期间在家中进行。 A) 将两种设备的测量结果与接近 1 的相关斜率和 R 平方系数进行比较。B) 记录结果并分析其变异性。试点研究证明了 Breezing Med 设备易于非专业人士在家使用的优势，这使得该设备成为与家庭体重管理相关的远程医疗应用的有价值的设备。该结果表明，MGC Ultima CPX™ 和 Breezing Med 在 REE 测量方面基本等效；以及该设备在当前 COVID-19 大流行情况下进行代谢评估的优势，对于身体活动能力受损的人以及生活在农村地区或面临身体无法获得护理的障碍的人来说。
Resting Energy Expenditure (REE) quantitatively describes the calories used to support body function (e.g. breathing, blood circulation, etc.) at resting condition. Assessment of the REE is essential for successful weight management and the understanding of metabolic health. REE is typically determined via indirect calorimetry. Current biomedical indirect calorimetry technologies, utilizing assessment of oxygen consumption (VO2) and carbon dioxide production (VCO2) rates (which are typically in the form factor of a metabolic cart) are bulky and require on-site calibration and/or trained professionals to operate. We introduce a novel wearable medical device with FDA clearance to determine REE accurately, portable, and user-friendly format, which can be used both by health professionals in a clinical environment and by the patient at home. Previously, we have reported the validation of Breezing Med (also named as Breezing Pro™) through Douglas Bag Method, a gold standard for gas exchange measurement, and excellent agreement has been found between the two methods for the determination of REE, VO2, and VCO2 rates. Now we present the validation of Breezing Med against Medical Graphics (MGC) CPX Ultima™, a FDA 510k cleared metabolic cart, which principle is based on breath-by-breath analysis. In addition, we present Breezing Med as a tool for daily measurement of metabolic rate by the lay person at home. A) The validation study was executed via parallel measurement of 20 healthy participants under resting conditions using both the Breezing Med and the MGC Ultima CPX™ (10 min test). B) Breezing Med measurements were carried out by six subjects at home during stay-at-home order due to COVID-19 for 30 days. A) The resulting measurements from both devices was compared with correlation slope’s and R-squared coefficients close to 1. B) Results were recorded and analyzed for variability. The pilot study demonstrated the advantage of Breezing Med device to be easy-to-use at home by lay people, which make the valuable device for telemedicine applications related to weight management from home. This result shows that the MGC Ultima CPX™ and Breezing Med are substantially equivalent for REE measurement; and an advantage of this device for metabolic assessment under the current COVID-19 pandemic situation, for people with impaired physical mobility, and for those who lives in rural areas or face impediments that limit physical access to care.
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影响因子：
7.1
作者：
SCHULZ, LO;SCHOELLER, DA
通讯作者：
SCHOELLER, DA
DOI：
10.1111/hex.13148
发表时间：
2021-03
期刊：
Health expectations : an international journal of public participation in health care and health policy
影响因子：
--
作者：
Cliffe M;Di Battista E;Bishop S
通讯作者：
Bishop S
DOI：
10.1016/j.cub.2015.12.046
发表时间：
2016-02-08
期刊：
Current biology : CB
影响因子：
--
作者：
Pontzer H;Durazo-Arvizu R;Dugas LR;Plange-Rhule J;Bovet P;Forrester TE;Lambert EV;Cooper RS;Schoeller DA;Luke A
通讯作者：
Luke A
影响因子：
4.5
作者：
Komura K;Nakae S;Hirakawa K;Ebine N;Suzuki K;Ozawa H;Yamada Y;Kimura M;Ishii K
通讯作者：
Ishii K
影响因子：
--
作者：
Hayhurst, Chris
通讯作者：
Hayhurst, Chris