Fibroids and Urinary Symptoms Study (FUSS)
Fibroids and Urinary Symptoms Study (FUSS)
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DOI：
10.1097/spv.0000000000000967
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发表时间：
2021-02-01
影响因子：
1.6
通讯作者：
Kenton, Kimberly
中科院分区：
文献类型：
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作者：
Bochenska, Katarzyna;Lewitt, Tessa;Kenton, Kimberly
该研究的目的是描述寻求子宫肌瘤治疗的女性的骨盆底和泌尿系统症状，并探讨子宫/肌瘤大小与骨盆底症状之间的关系。在一个学术中心寻求治疗子宫肌瘤的妇女参加了这项横断面研究。所有参与者均接受盆腔成像，并完成子宫肌瘤症状和健康相关生活质量问卷（UFS-QOL）的症状严重程度子量表和骨盆底不适量表（PFDI-20）。结果纳入195名女性，平均年龄41 ± 6岁，体重指数29 ± 7 kg/m2。在这个队列中，58%被确定为黑人，38%至少有一次阴道分娩。女性将盆腔疼痛（68%）、性交困难（37%）和尿失禁（31%）归因于肌瘤。平均+/- SD UFS-QOL评分为48.7 +/- 25.4，63%的参与者报告至少“有点困扰”骨盆区域的紧绷/压力，60%的参与者报告频繁的日间排尿，47%的参与者报告排尿困难。平均PFDI-20评分为45.5 +/- 31.9。女性报告至少“有点困扰”骨盆沉重/迟钝（60%），尿频（56%），骨盆疼痛或不适（48%），膀胱排空不完全（43%）。PFDI-20和UFS-QOL评分与子宫体积（r = 0.12，P = 0.12; r = 0.06，P = 0.44）或肌瘤大小（r = 0.09，P = 0.26; r = 0.01，P = 0.92）无关。结论：接受子宫肌瘤评估和治疗的女性报告有较高比例的盆底症状，尤其是尿频和盆腔压力。子宫大小及肌瘤大小与盆底症状困扰无关。
ObjectiveThe aims of the study were to characterize pelvic floor and urinary symptoms in women seeking treatment for uterine fibroids and to explore the association between uterine/fibroid size and pelvic floor symptoms. MethodsWomen seeking treatment for uterine fibroids at a single academic center were enrolled in this cross-sectional study. All participants underwent pelvic imaging and completed the Symptom Severity Subscale of the Uterine Fibroid Symptom and Health-Related Quality of Life Questionnaire (UFS-QOL) and the Pelvic Floor Distress Inventory (PFDI-20). ResultsOne hundred ninety-five women with a mean age of 41 +/- 6 years and body mass index of 29 +/- 7 kg/m(2) were included. In this cohort, 58% identified as Black and 38% had at least 1 vaginal delivery. Women attributed pelvic pain (68%), dyspareunia (37%), and urinary incontinence (31%) to their fibroids. The mean +/- SD UFS-QOL score was 48.7 +/- 25.4, and 63% of participants reported being at least "somewhat bothered" by tightness/pressure in pelvic area, 60% by frequent daytime urination, and 47% by nocturia. The mean PFDI-20 score was 45.5 +/- 31.9. Women reported being at least "somewhat bothered" by heaviness/dullness in the pelvis (60%), frequent urination (56%), pelvic pain or discomfort (48%), and sensation of incomplete bladder emptying (43%). The PFDI-20 and UFS-QOL scores were not correlated with uterine volume (r = 0.12, P = 0.12, and r = 0.06, P = 0.44) or fibroid size (r = 0.09, P = 0.26, and r = 0.01, P = 0.92). ConclusionsWomen presenting for evaluation and treatment of fibroids report high rates of pelvic floor symptoms, particularly urinary frequency and pelvic pressure. However, uterine size and fibroid size are not associated with pelvic floor symptom bother.