Central Nervous System: State of the Art Understanding Diffu- Sion Mr Imaging Tech- Niques: from Scalar Diffusion-weighted Imaging to Diffusion Tensor Imaging and beyond 1
Central Nervous System: State of the Art Understanding Diffu- Sion Mr Imaging Tech- Niques: from Scalar Diffusion-weighted Imaging to Diffusion Tensor Imaging and beyond 1
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通讯作者：
P. Hagmann;L. Jonasson;P. Maeder;J. Thiran;V. Wedeen;R. Meuli
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作者：
P. Hagmann;L. Jonasson;P. Maeder;J. Thiran;V. Wedeen;R. Meuli
脑的白色物质的复杂结构组织可以用先进的扩散磁共振（MR）成像方案在体内非常详细地描绘。扩散磁共振成像技术越来越多样化，从最简单和最常用的技术-表观扩散系数值的映射-到更复杂的技术，如扩散张量成像，q球成像，扩散谱成像和纤维束成像。所获得的结构信息的类型根据所使用的技术而不同。为了充分理解弥散磁共振成像的工作原理，熟悉脑中水扩散的物理原理和每种成像技术的概念基础是有帮助的。有关硬件和采集时间的特定技术要求的知识，以及每种技术的优点、局限性和潜在的解释缺陷，尤其有用。
The complex structural organization of the white matter of the brain can be depicted in vivo in great detail with advanced diffusion magnetic resonance (MR) imaging schemes. Diffusion MR imaging techniques are increasingly varied, from the simplest and most commonly used technique—the mapping of apparent diffusion coefficient val-ues—to the more complex, such as diffusion tensor imaging, q-ball imaging, diffusion spectrum imaging, and tractography. The type of structural information obtained differs according to the technique used. To fully understand how diffusion MR imaging works, it is helpful to be familiar with the physical principles of water diffusion in the brain and the conceptual basis of each imaging technique. Knowledge of the technique-specific requirements with regard to hardware and acquisition time, as well as the advantages, limitations, and potential interpretation pitfalls of each technique, is especially useful.