Burden of valvular heart diseases: a population-based study
Burden of valvular heart diseases: a population-based study
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DOI：
10.1016/s0140-6736(06)69208-8
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发表时间：
2006-09-16
期刊：
影响因子：
168.9
通讯作者：
Enriquez-Sarano, Maurice
中科院分区：
文献类型：
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作者：
Nkomo, Vuyisile T.;Gardin, Julius M.;Enriquez-Sarano, Maurice
背景心脏瓣膜病通常不被认为是一个主要的公共卫生问题。我们的目的是评估他们的患病率和对总生存率的影响，在一般population.Methods，我们汇集了基于人群的研究，以获得数据为11911随机选择的成年人从一般人群中进行了前瞻性评估与超声心动图。我们还分析了16 501名成年人的社区研究的数据，他们已被评估的临床指征echocardios.Findings在一般人群组，中度或重度瓣膜疾病被确定在615名成年人。男性和女性之间此类疾病的发生率没有差异（p=0.90）。患病率随着年龄的增长而增加，从18-44奥尔兹的0.7%（95%CI 0.5-1.0）增加到75岁及以上组的13.3%（11.7-15.0）（p
Background Valvular heart diseases are not usually regarded as a major public-health problem. Our aim was to assess their prevalence and effect on overall survival in the general population.Methods We pooled population-based studies to obtain data for 11911 randomly selected adults from the general population who had been assessed prospectively with echocardiography. We also analysed data from a community study of 16 501 adults who had been assessed by clinically indicated echocardiography.Findings In the general population group, moderate or severe valve disease was identified in 615 adults. There was no difference in the frequency of such diseases between men and women (p=0.90). Prevalence increased with age, from 0.7% (95% CI 0.5-1.0) in 18-44 year olds to 13.3% (11.7-15.0) in the 75 years and older group (p