Molecular genetics of dopa decarboxylase and biogenic amines in Drosophila.
Molecular genetics of dopa decarboxylase and biogenic amines in Drosophila.
复制标题
果蝇多巴脱羧酶和生物胺的分子遗传学。
DOI：
10.1002/dvg.1020100312
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发表时间：
1989
期刊：
影响因子：
--
通讯作者：
Hirsh,J
中科院分区：
文献类型：
--
作者：
Hirsh,J
该基因编码果蝇中多巴脱羧酶的两种异构体，这些基因产物催化生物胺血清张力素和多巴胺合成的最后步骤。本文综述了Ddc在转录和选择性剪接水平上的组织和细胞特异性调控的最新进展。此外，还讨论了与了解生物胺在果蝇神经生理学中的作用有关的结果。
The geneDdcencodes two isoforms of the enzyme dopa decarboxylase inDrosophila.These gene products catalyze the final steps in the synthesis of the biogenic amines sero‐tonin and dopamine. This article summarizes recent progress in understanding the tissue‐ and cell‐specific regulation ofDdc, which occurs at both the transcription and alternate splicing levels. In addition, results that are pertinent to understanding the roles of biogenic amines in the neurophysiology ofDrosophilaare discussed.