N-benzyl-norephedrine derivatives as new, efficient ligands for ruthenium-catalyzed asymmetric transfer hydrogenation of functionalized ketones
N-benzyl-norephedrine derivatives as new, efficient ligands for ruthenium-catalyzed asymmetric transfer hydrogenation of functionalized ketones
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DOI：
10.1016/s0957-4166(99)00465-6
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发表时间：
1999-10-29
影响因子：
--
通讯作者：
Bulliard, M
中科院分区：
文献类型：
--
作者：
Everaere, K;Carpentier, JF;Bulliard, M
显著的催化活性在[RuCl 2（η（6）-芳烃）]（2）和（1 S，2 R）-去甲麻黄碱如N-苄基-去甲麻黄碱和N-（4-联苯基）甲基-去甲麻黄碱。(C)1999 Elsevier Science Ltd.保留所有权利。
Significant catalytic activities (up to 600 h(-1) at 20 degrees C) and enantiomeric excesses ranging from 56 to 89% for the asymmetric transfer hydrogenation of beta-ketoesters, methoxyacetone and 2-acetylpyridine to the corresponding alcohols are achieved in the presence of catalytic combinations of [RuCl2(eta(6)-arene)](2) and N-substituted derivatives of(1S,2R)-norephedrine such as N-benzyl-norephedrine and N-(4-biphenyl)methyl-norephedrine. (C) 1999 Elsevier Science Ltd. All rights reserved.