Assessing the effects of diurnal variation on the composition of human parotid saliva: Quantitative analysis of native peptides using iTRAQ reagents
Assessing the effects of diurnal variation on the composition of human parotid saliva: Quantitative analysis of native peptides using iTRAQ reagents
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DOI：
10.1021/ac050161r
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发表时间：
2005-08-01
影响因子：
7.4
通讯作者：
Fisher, SJ
中科院分区：
文献类型：
--
作者：
Hardt, M;Witkowska, HE;Fisher, SJ
唾液成分的变化与疾病易感性、疾病状态或两者相关。然而，由于昼夜节律或日变化的腺体特异性影响，唾液用于诊断目的变得复杂。我们最近鉴定了一组肽
Changes in salivary composition correlate with disease susceptibility, disease state, or both. However, use of saliva for diagnostic purposes is complicated by the gland-specific effects of circadian rhythm or diurnal variation. We recently characterized a suite of peptides in the