EFFECTS OF SILVER ON ADHERENCE OF BACTERIA TO URINARY CATHETERS - IN-VITRO STUDIES
EFFECTS OF SILVER ON ADHERENCE OF BACTERIA TO URINARY CATHETERS - IN-VITRO STUDIES
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DOI：
10.1007/bf00294518
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发表时间：
1995-01-01
影响因子：
2.6
通讯作者：
AHEARN, DG
中科院分区：
文献类型：
--
作者：
GABRIEL, MM;SAWANT, AD;AHEARN, DG
大肠埃希菌、奇异变形杆菌、铜绿假单胞菌、粪肠球菌和肺炎克雷伯菌菌株（主要来自复杂性尿路感染）显示，与乳胶或硅胶导管相比，银处理硅胶或乳胶导管的粘附性降低。在2小时或18小时的细胞粘附到导管的相对程度，如放射性标记细胞测定所示，与生长速率降低测定和扫描电子显微镜数据基本一致。为了缓解压力。大肠杆菌中，细胞疏水性与粘附程度之间的相关性不显著。抗生素耐药性（四环素、磺胺嘧啶、新霉素、卡那霉素）和银耐药性不相关。放射性标记粘附程序为评价银处理导管的相对抗菌效力提供了定量方法。
Strains of Escherichia coli, Proteus mirabilis, Pseudomonas aeruginosa, Enterococcus faecalis, and Klebsiella pneumoniae, mostly from complicated urinary tract infections, showed reduced adherence to silver-treated silicone or latex catheters as compared with latex or silicone catheters. The relative degrees of cell adherence to catheters at 2 h or 18 h, as indicated by radiolabeled cell assays, were in general agreement with growth rate-reduction assays and scanning-electron-microscopy data. For strains off. coli, the correlation between cell hydrophobicity and degree of adherence to catheters was not significant. Antibiotic resistance (tetracycline, sulfathiazine, neomycin, kanamycin) and silver resistance were not associated. The radiolabel adherence procedure provided a quantitative method for evaluating the relative antimicrobial efficacy of silver-treated catheters.