Effects of sintering temperature over 1,300 degrees C on the physical and compositional properties of porous hydroxyapatite foam.
Effects of sintering temperature over 1,300 degrees C on the physical and compositional properties of porous hydroxyapatite foam.
复制标题
1300℃以上的烧结温度对多孔羟基磷灰石泡沫物理和成分性能的影响。
DOI：
--
复制
发表时间：
2006
影响因子：
2.5
通讯作者：
M. Nakagawa
中科院分区：
文献类型：
--
作者：
M. Munar;K. Udoh;K. Ishikawa;S. Matsuya;M. Nakagawa
多孔羟基磷灰石(HAP)泡沫允许三维(3D)结构，具有完全相互连接的毛孔，以及良好的组织响应和良好的骨传导性。因此，它被认为是一种很好的骨再生支架材料和人工骨替代材料。为了制备更好的多孔HAP泡沫，需要改善物理和结构性能以及更高的骨传导性。在本研究中，采用从1300℃到1550℃的高温烧结，研究了烧结温度对多孔HAP泡沫的物理和化学性能的影响。多孔HAP泡沫的机械强度随着烧结温度的升高而增加，在1525℃时达到最大值，当烧结温度进一步提高到1550℃时，机械强度略有下降，形成了α-磷酸三钙(α-TCP)，从而形成了两相磷酸钙泡沫。据报道，由α-磷酸三钙和羟基磷灰石组成的双相磷酸钙具有比单独的羟基磷灰石更高的骨传导性。因此，我们建议多孔HAP泡沫塑料的烧结温度为1,500-1,550℃，因为这种条件提供了双相磷酸钙成分最理想的物理性能。
Porous hydroxyapatite (HAP) foam permits three-dimensional (3D) structure with fully interconnecting pores as well as excellent tissue response and good osteoconductivity. It is therefore thought to be a good candidate as scaffold material for bone regeneration and as a synthetic bone substitute material. To fabricate better porous HAP foam, improved physical and structural properties as well as higher osteoconductivity are desired. In the present study, the effects of sintering temperature on the physical and compositional properties of porous HAP foam were evaluated by employing high sintering temperature starting at 1,300 degrees C up to 1,550 degrees C. The mechanical strength of porous HAP foam increased with sintering temperature to reach the maximum value at 1,525 degrees C, then decreased slightly when sintering temperature was further increased to 1,550 degrees C. Alpha tricalcium phosphate (alpha-TCP) was formed, and thus the porous HAP foam became biphasic calcium phosphate. Biphasic calcium phosphate consisting of both alpha-TCP and HAP had been reported to show higher osteoconductivity than HAP alone. We therefore recommend 1,500-1,550 degrees C as the sintering temperature for porous HAP foam since this condition provided the most desirable physical properties with biphasic calcium phosphate composition.