Prenatal Exposures to Environmental Chemicals and Children's Neurodevelopment: An Update.
Prenatal Exposures to Environmental Chemicals and Children's Neurodevelopment: An Update.
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DOI：
10.5491/shaw.2013.4.1.1
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发表时间：
2013-03
影响因子：
3.5
通讯作者：
Bellinger DC
中科院分区：
文献类型：
--
作者：
Bellinger DC
这篇综述调查了最近的文献在怀孕期间的化学品暴露的神经发育的影响。审查主要侧重于最近引起关注的化学品，包括邻苯二甲酸酯、双酚A、多溴二苯醚和全氟化合物，但也涉及调查历史较长的化学品，包括空气污染物、铅、甲基汞、锰、砷和有机磷农药。对于最近关注的一些化学品，现有文献尚未提供关于神经发育毒性的有力结论。在这种情况下，确定了研究之间的分歧点，并就解决不一致的方法提出了建议，包括使表示接触和评估结果的方法更加标准化。
This review surveys the recent literature on the neurodevelopmental impacts of chemical exposures during pregnancy. The review focuses primarily on chemicals of recent concern, including phthalates, bisphenol-A, polybrominated diphenyl ethers, and perfluorinated compounds, but also addresses chemicals with longer histories of investigation, including air pollutants, lead, methylmercury, manganese, arsenic, and organophosphate pesticides. For some chemicals of more recent concern, the available literature does not yet afford strong conclusions about neurodevelopment toxicity. In such cases, points of disagreement among studies are identified and suggestions provided for approaches to resolution of the inconsistencies, including greater standardization of methods for expressing exposure and assessing outcomes.