Evaluation of pain in patients with oral squamous cell carcinoma
Evaluation of pain in patients with oral squamous cell carcinoma
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DOI：
10.1016/j.jpain.2004.09.002
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发表时间：
2004-11-01
期刊：
影响因子：
4
通讯作者：
Schmidt, BL
中科院分区：
文献类型：
--
作者：
Connelly, ST;Schmidt, BL
在这项研究中，我们开发并测试了一种新的疼痛问卷，以衡量口腔鳞状细胞癌患者所经历的疼痛。问卷由患者在视觉模拟量表上评定的8个问题组成。患者在手术治疗前首次就诊时完成问卷调查。所有患者均未服用止痛药。然后对这些反应进行评分，并与患者数据和病理报告一起汇编。在15份完成的问卷中，14名患者报告了一定程度的疼痛功能限制（平均值，46.6 +/- t 25.2，量表为0至100 mm）。平均而言，患者经历了明显更高的功能相关，而不是自发，疼痛强度和尖锐性。男性（n = 8）与女性（n = 7）相比，功能相关疼痛强度和尖锐度显著更高。有一个很强的相关性之间的淋巴结疾病和自发的强度，锐度，悸动，和整体功能restrictions.Perspective水平的增加：本研究的结果表明，口腔癌疼痛的异质性和功能依赖。我们在这项研究中开发的问卷将允许在未来的研究中疼痛参数和特定肿瘤生物学之间的相关性。(C)2004年，美国疼痛协会。
In this study we have developed and tested a novel pain questionnaire to measure the pain experienced by patients with oral squamous cell carcinoma. The questionnaire consisted of 8 questions rated by the patient on a visual analog scale. Patients completed the questionnaire at the time of initial presentation before surgical treatment. None of the patients were taking analgesics. The responses were then scored and compiled with patient data and pathology reports. Of the 15 completed questionnaires, 14 patients reported some level of functional restriction from pain (mean, 46.6 +/- t 25.2, scale of 0 to 100 mm). On average, patients experienced significantly higher function-related, rather than spontaneous, pain intensity and sharpness. Men (n = 8) had a significantly higher level of function-related pain intensity and sharpness than women had (n = 7). There was a strong correlation between nodal disease and increased levels of spontaneous intensity, sharpness, throbbing, and overall functional restriction.Perspective: The results of this study indicate the heterogeneous nature and function dependence of oral cancer pain. The questionnaire we have developed in this study will allow for correlations between pain parameters and specific tumor biology in future studies. (C) 2004 by the American Pain Society.