What influences participation in genetic carrier testing? Results from a discrete choice experiment
What influences participation in genetic carrier testing? Results from a discrete choice experiment
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DOI：
10.1016/j.jhealeco.2005.09.002
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发表时间：
2006-05-01
影响因子：
3.5
通讯作者：
Louviere, Jordan J.
中科院分区：
文献类型：
--
作者：
Hall, Jane;Fiebig, Denzil G.;Louviere, Jordan J.
这项研究探讨了影响参与基因检测计划和接受多种检测的因素。家族性黑蒙病和囊性纤维化都是遗传决定的隐性疾病，在不同人群中具有不同的严重程度、治疗可用性和患病率。我们使用了一个离散的选择实验与一般社区和德系犹太人的样本，数据进行了分析，使用多项式logit与随机系数。虽然犹太受访者更有可能接受检测，但两组人在做出基因检测选择时，似乎都在做出非常相似的权衡。(c)2005 Elsevier B.V.保留所有权利。
This study explores factors that influence participation in genetic testing programs and the acceptance of multiple tests. Tay Sachs and cystic fibrosis are both genetically determined recessive disorders with differing severity, treatment availability, and prevalence in different population groups. We used a discrete choice experiment with a general community and an Ashkenazi Jewish sample; data were analysed using multinomial logit with random coefficients. Although Jewish respondents were more likely to be tested, both groups seem to be making very similar tradeoffs across attributes when they make genetic testing choices. (c) 2005 Elsevier B.V. All rights reserved.