BRONCHOSPASM INDUCED BY INTRAVENOUS ADENOSINE
BRONCHOSPASM INDUCED BY INTRAVENOUS ADENOSINE
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DOI：
10.1177/096032719401300407
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发表时间：
1994-04-01
影响因子：
2.8
通讯作者：
RICHARDS, R
中科院分区：
文献类型：
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作者：
DRAKE, I;ROUTLEDGE, PA;RICHARDS, R
众所周知，吸入腺苷会引起支气管收缩，但迄今为止只有一例静脉注射在26名接受该药物治疗的患者中，腺苷导致两名患者（仅有的两名哮喘患者）支气管收缩。在一名受试者中，吸入后的反应持续时间比先前报道的要长得多我们认为腺苷可能加重某些哮喘患者的支气管痉挛，该组应考虑替代两种治疗室上性心动过速的方法。
1 Adenosine is well known to cause bronchoconstriction when inhaled, but to date there has been only one report following the intravenous route.2 Adenosine caused bronchoconstriction in two patients (the only two with asthma) out of 26 treated with the drug. In one subject the duration of response was much longer than previously reported following inhalation.3 We suggest that adenosine may aggravate bronchospasm in some asthmatics and alternative two treatments for supraventricular tachycardia should 26 be considered in this group.