Population consequences of mutational events: effects of antibiotic resistance on the r/K trade-off
Population consequences of mutational events: effects of antibiotic resistance on the r/K trade-off
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DOI：
10.1007/s10682-009-9302-8
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发表时间：
2010-01-01
影响因子：
1.9
通讯作者：
Kassen, Rees
中科院分区：
文献类型：
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作者：
Fitzsimmons, Jay M.;Schoustra, Sijmen E.;Kassen, Rees
突变事件对种群动态有什么影响？这个生态进化问题不仅与基本的生物学理论有关，而且与保护应用有关。我们评估了细菌荧光假单胞菌菌株之间的最大种群增长率（r（max））和承载力（K）之间的关系。65个菌株中的每一个都与它们的共同祖先不同，一个自然获得的表型变化赋予抗生素抗性，由一个单一的突变事件引起，并且每个菌株都在四个环境中隔离生长。我们没有发现r（max）和K之间存在权衡的证据。相反，具有快速生长速率的菌株也具有高承载能力，菌株与环境之间的相互作用很小。我们的结论是，广泛的变化，在整体健身造成的单一突变事件可能掩盖任何人口权衡可能存在。
What are the effects of a mutational event on population dynamics? This eco-evolutionary question has relevance not only to basic biological theories but also to conservation applications. We evaluated the relationship between maximum population growth rate (r (max)) and carrying capacity (K) among strains of the bacterium Pseudomonas fluorescens. Each of 65 strains differed from their common ancestor by one naturally acquired phenotypic change conferring antibiotic resistance, brought about by a single mutational event, and each was grown in isolation in four environments. We found no evidence of a trade-off between r (max) and K. Rather, strains with rapid growth rates also had high carrying capacity, with little interaction between strain and environment. We conclude that the extensive variation in overall fitness resulting from single mutational events likely masks whatever population trade-offs may exist.