Some normal and abnormal behavioral syndromes due to transmitter gating of opponent processes.

Some normal and abnormal behavioral syndromes due to transmitter gating of opponent processes.
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由于对手进程的发射器门控而导致的一些正常和异常行为综合症。

DOI:
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发表时间:
1984
影响因子:
10.6
通讯作者:
S. Grossberg
S. Grossberg
中科院分区:
医学1区
文献类型:
--
作者:
S. Grossberg

文献摘要

被引文献

相似文献

长期以来,对立过程一直被认为是神经回路的基本组成部分。本文描述了对立过程的特性,其中相位线索和张力唤醒是由缓慢积累的化学递质控制的。这些对立的过程被称为门控偶极子。门控偶极电路表现出形式属性综合症,可用于支持或否定其在复杂行为数据体中的生成作用。各种正常和异常的行为和生理数据显示出与门控偶极子电路类似的特性。这些数据包括细胞内适应、习惯化和反弹;意外事件引起的不适应和注意力重置;欠唤醒或过度唤醒导致的倒U属性;少年多动;帕金森症;贪食的饮食;简单的精神分裂症;镇痛剂如内啡肽、脑电刺激和大声噪音的作用;耐受性戒断症状及其预防的新方法正常和异常的昼夜节律,如嗜睡症和躁狂抑郁性精神病;强化、驱动和激励信号的处理。总结了从门控偶极电路中得到的一些数据预测。
Opponent processes have long been known to be a basic building block of neural circuits. This article describes properties of opponent processes in which phasic cues and tonic arousal are gated by slowly accumulating chemical transmitters. These opponent processes are called gated dipoles. Gated dipole circuits exhibit syndromes of formal properties that can be used to support or dis-confirm their generative role in a complex body of behavioral data. A wide variety of normal and abnormal behavioral and physiological data exhibit properties analogous to those of gated dipole circuits. These include data about intracellular adaptation, habituation, and rebound; dishabituation and attentional reset by an unexpected event; inverted U properties due to underarousal or overarousal; juvenile hyperactivity; parkinsonism; hyperphagic eating; simple schizophrenia; actions of analgesic agents such as endorphins, electrical brain stimulation, and loud noise; tolerance-withdrawal symptoms, and a new approach to their prevention; normal and abnormal circadian rhythms, as in narcolepsy and manic-depressive psychosis; processing of reinforcing, drive, and motivating signals. Some data predictions derived from gated dipole circuits are also summarized.