Chemical constituents from the stems of Celastrus orbiculatus
Chemical constituents from the stems of Celastrus orbiculatus
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DOI：
10.3724/sp.j.1009.2012.00279
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发表时间：
2012-07-01
影响因子：
4.6
通讯作者：
Wang Qiang
中科院分区：
文献类型：
--
作者：
Li Jian-Juan;Yang Jie;Wang Qiang
目的：研究南蛇藤茎的化学成分。方法：采用硅胶柱层析、Sephadex LH-20凝胶柱层析、ODS柱层析等方法分离纯化。根据理化性质和光谱数据鉴定了它们的结构。研究结果：共分离得到11个化合物，分别鉴定为3，3 β-羟基-2-氧代-12-烯-22，29-内酯（1），2，6-二甲氧基苯醌（2），3-氧代-12-烯-28-酸（3），3-氧代-24-降冰片-12-烯-28-酸（4），23-羟基桦木酸（5），香草酸（6），23-羟基-3-氧代藜芦-12-烯-28-酸（7），胡萝卜酸（8），油酸（9），β-谷甾醇（10），β-胡萝卜甾醇（11）。结论：化合物1为新的三萜类化合物，化合物2-5和7为首次从该属植物中分离得到，化合物8和9为首次从该植物中分离得到。
AIM: To investigate the chemical constituents from the stems of Celastrus orbiculatus Thunb.. METHODS: The chemical constituents were isolated and purified by silica gel, Sephadex LH-20 and ODS column chromatography. Their structures were elucidated on the basis of physical characteristics and spectral data. RESULTS: Eleven compounds were obtained and their structures were identified as 3,3 beta-hydroxy-2-oxoolean-12-ene-22, 29-lactone (1), 2, 6-dimethoxybenzoquinone (2), 3-oxoolean-12-en-28-oic acid (3), 3-oxo-24-norolean-12-en-28-oic acid (4), 23-hydroxybetulonic acid (5), vanillic acid (6), 23-hydroxy-3-oxoolean-12-en-28-oic acid (7), syringic acid (8), oleanolic acid (9), beta-sitosterol (10), beta-daucosterol (11). CONCLUSION: Compound 1 is a new triterpene; compounds 2-5 and 7 were isolated from this genus for the first time and compounds 8 and 9 were firstly isolated from this plant.