Assessing growth of infants with chylothorax receiving fortified skimmed human breast milk.
Assessing growth of infants with chylothorax receiving fortified skimmed human breast milk.
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DOI：
10.1002/ncp.10887
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发表时间：
2023-02
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影响因子：
--
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中科院分区：
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--
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了解脱脂母乳(SHM)如何用于乳糜胸的婴儿，以在接受母乳的同时支持足够的体重增加和营养。乳糜胸的传统营养管理是限制长链甘油三酯(LCT)，并提供高中链甘油三酯(MCT)的饮食。需要从母乳向配方奶粉过渡，以提供阻止乳胶堆积所需的MCT/LCT比率。虽然SHM可能会为患有乳糜胸的婴儿提供合适的脂肪含量，但之前的研究表明，接受SHM治疗的婴儿发育缓慢。证明接受高MCT婴儿配方奶粉强化的SHM的婴儿将有与年龄相适应的生长，而不会再次积聚乳酪。2017-9年间，对之前接受母乳喂养并过渡到强化SHM的被诊断为乳糜胸的足月儿进行了生长和乳酪再积累的监测。使用标准配方给6名服用高MCT婴儿配方奶粉的强化SHM的婴儿没有乳糜重积聚，6名研究患者中有5名体重增加。婴儿平均体重增加30.5克/天(±19.5)，体重z分数平均提高+0.29(±0.33)。加强型SHM是一种安全的治疗方案，可为乳糜胸婴儿提供充足的营养，使其体重适当增加。
To learn how skimmed human milk (SHM) can be used in infants with chylothorax to support adequate weight gain and nutrition while receiving human milk. Traditional nutrition management for chylothorax is to limit long chain triglycerides (LCT) and provide a diet high in medium chain triglycerides (MCT). Transition from human milk to formula has been required in order to provide the MCT/LCT ratio required to stop the accumulation of chyle. While SHM may provide the right fat content for a baby with chylothorax, previous studies have shown slow growth in infants receiving SHM. Demonstrate that infants receiving SHM fortified with high MCT infant formula will have age appropriate growth without re-accumulation of chyle. Between 2017–9, term infants with the diagnosis of chylothorax who were previously receiving human milk and transitioned to fortified SHM were monitored for growth and re-accumulation of chyle. The six infants who were prescribed fortified SHM with high MCT infant formula using standardized recipes did not show re-accumulation of chyle and showed positive weight gain in five of the six study patients. The infants gained a mean weight of 30.5 gm/day (±19.5) and their weight z scores improved by a mean of +0.29 (±0.33). Fortified SHM is a safe treatment option which can provide adequate nutrition for the infant with chylothorax to gain weight appropriately for age.
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